The hard part about opening a hole in the proof of the Poincaré conjecture is that Grigori Perelman will come out of retirement to try to fix it by drawing a loop around the hole and contracting it to a point.

"Millennium Problems", by Randall Munroe, licensed under Creative Commons Attribution-NonCommercial 2.5 License

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The hard part about opening a hole in the proof of the Poincaré conjecture is that Grigori Perelman will come out of retirement to try to fix it by drawing a loop around the hole and contracting it to a point.